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Fig. 8 | Respiratory Research

Fig. 8

From: Biochemical and transcriptomic evaluation of a 3D lung organoid platform for pre-clinical testing of active substances targeting senescence

Fig. 8

Scheme of the 3D lung organoid platform for pre-clinical testing of active substances. In the 96-well platform different endpoints can be measured in one assay run. Fluorescence measurements and microscopic images can be recorded directly in the plate. Various factors such as cytokines can be measured in the supernatants. Numerous methodologies such as biochemical assays and single cell sequencing can be carried out with isolated organoids

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