Table 1 Clinical, demographic, and sample characteristics of pwCF (n = 16) on/off ETI therapy (n = 7/9)
Subject ID | ETI | Days on ETI | Period (days) between the first sample and ETI | Samples collected | BMI | Gender | ppFEV1 PP (%) | FVC PP (%) | Pathogen cultures (Sputum) |
|---|---|---|---|---|---|---|---|---|---|
001 | No | – | 104 | 18.9 | F | 54.4 | 73.8 | – | |
002 | No | – | 36 | 27.5 | M | 54.8 | 73.1 | – | |
003 | No | – | 114 | 23.0 | M | 38.7 | 48.3 | Pa, Sa | |
004 | No | – | 75 | 20.6 | F | 52.9 | 63.4 | Pa, Ac | |
005 | No | – | 190 | 29.0 | M | 69.6 | 91.1 | Steno | |
006 | No | – | 90 | 18.5 | F | 52.0 | 78.4 | – | |
007 | No | – | 17 | 30.2 | F | 50.0 | 60.0 | Pa, Sa, Ac, Strep | |
008 | No | – | 20 | 21.5 | F | 52.0 | 70.0 | Pa, Sa | |
009 | No | – | 15 | 22.1 | M | 40.0 | 66.0 | Pa | |
010 | Yes | 537 | 277 | 18 | 27.3 | F | 111.0 | 114.0 | Pa, Sa |
011 | Yes | 286 | 163 | 40 | 27.9 | M | 79.0 | 100.0 | Pa, Sa, Steno, Strep |
012 | Yes | 454 | 226 | 20 | 20.2 | F | 67.0 | 84.0 | Pa, Sa, Strep |
013 | Yes | 453 | 345 | 13 | 23.3 | F | 72.0 | 75.0 | Pa, Sa, Bc, |
014 | Yes | 227 | 103 | 35 | 20.7 | F | 53.0 | – | Bc |
015 | Yes | 426 | 326 | 15 | 22.4 | F | 52.0 | 70.0 | Pa |
016 | Yes | 377 | 210 | 21 | 23.2 | F | 101.0 | 107.0 | Pa, Sa |