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Fig. 2 | Respiratory Research

Fig. 2

From: Longitudinal microbial and molecular dynamics in the cystic fibrosis lung after Elexacaftor–Tezacaftor–Ivacaftor therapy

Fig. 2

The average microbiome and metabolome diversity of subjects in this study. A Average change in the alpha-diversity (Shannon index) of lung microbiome and metabolome of pwCF off/on ETI treatment per day. Square shapes represent individuals who did not take ETI, while circular shapes are associated with those who did take ETI. B Average of the beta-diversity of the lung microbiome and metabolome of pwCF before and after ETI per day. Weighted UniFrac distance was used for microbiome data and Bray–Curtis dissimilarity for metabolome data. P-values obtained from the Wilcoxon test are displayed. Scatterplots of the predicted vs. observed C microbiome and D metabolome association with the time in days since pwCF started on ETI treatment. This data was obtained from RF regression analysis of each subject as well as their Pearson correlation tests

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Respiratory Research

ISSN: 1465-993X

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