Fig. 1

oxPL induces lung fibrosis in a CD36-dependent manner. Trichome stained lung sections (200x) from WT (A, C) or CD36-null (B, D) mice 14 days after intratracheal delivery of PBS (A, B) or oxPL (POVPC at 10 µg/gram) (C, D). E Hydroxyproline assay of lungs from WT and CD36-null mice 14 days after intratracheal instillation of oxPL or PBS control. n = 8–20/group. *p < 0.01 compared to WT mice treated with PBS. ** p < 0.05 compared to WT mice treated with oxPL