From: Deep learning prediction of hospital readmissions for asthma and COPD
Asthma | COPD | |||||
---|---|---|---|---|---|---|
Single Hx | Multiple Hx | p-val | Single Hx | Multiple Hx | p-val | |
Number | 1507 | 386 | 2542 | 1359 | ||
Age (years) | 41 (26–58) | 41 (24–57) | 0.47 | 72 (63–81) | 70 (60–79) | < 0.01 |
Female sex n (%) | 1023 (68) | 265 (69) | 0.82 | 1352 (53) | 560 (41) | < 0.01 |
Race n (%) | < 0.01 | < 0.01 | ||||
African American | 500 (33) | 169 (44) | 255 (10) | 245 (18) | ||
White | 652 (43) | 117 (30) | 2127 (84) | 1027 (76) | ||
Hispanic ethnicity n (%) | 363 (24) | 116 (30) | 0.02 | 127 (5) | 107 (8) | < 0.01 |
BMI (kg/m2) | 30.7 (25.3–37.2) | 29.8 (25.1–36.7) | 0.61 | 27.3 (22.6–33.2) | 28.0 (23.2–34.3) | < 0.01 |
Smoking status (n) | 1440 | 372 | 0.04 | 2435 | 1343 | < 0.01 |
Never n (%) | 806 (56) | 216 (58) | 214 (9) | 73 (5) | ||
Current n (%) | 275 (19) | 51 (14) | 633 (26) | 338 (25) | ||
Former n (%) | 359 (25) | 105 (28) | 1588 (65) | 932 (69) | ||
Length of Stay | 2 (2–4) | 2 (2–4) | 0.23 | 5 (3–8) | 4 (3–7) | < 0.01 |
ICU admission n (%) | 203 (13) | 64 (17) | 0.14 | 629 (25) | 251 (18) | < 0.01 |
Death within a year n (%) | 44 (3) | 4 (1) | 0.06 | 568 (22) | 153 (11) | < 0.01 |
Multiple comorbidities (> 1) | 870 (58) | 263 (70) | < 0.01 | 2196 (86) | 1271 (94) | < 0.01 |
Medications (n) | 1475 | 381 | 2510 | 1353 | ||
Albuterol | 1112 (75) | 370 (97) | < 0.01 | 1364 (54) | 1183 (87) | < 0.01 |
ICS | 226 (15) | 123 (32) | < 0.01 | 193 (8) | 243 (18) | < 0.01 |
ICS + LABA | 604 (41) | 288 (76) | < 0.01 | 1348 (54) | 1150 (85) | < 0.01 |
LAMA | 62 (4) | 60 (16) | < 0.01 | 874 (35) | 884 (65) | < 0.01 |
LTRA | 353 (24) | 220 (58) | < 0.01 | 206 (8) | 306 (23) | < 0.01 |
Antibiotic | 741 (50) | 252 (66) | < 0.01 | 2041 (81) | 1321 (98) | < 0.01 |
Nicotine replacement | 107 (7) | 52 (14) | < 0.01 | 405 (16) | 4040 (30) | < 0.01 |
Systemic steroids | 1073 (73) | 361 (95) | < 0.01 | 1738 (69) | 1295 (96) | < 0.01 |
CBC (n) | 627 | 150 | 1270 | 635 | ||
White blood cells | 9.6 (7.4–12.7) | 9.7 (7.1–12.1) | 0.69 | 9.9 (7.3–13.0) | 9.9 (7.6–12.8) | 0.96 |
Absolute neutrophil count | 6.7 (4.7–10.2) | 6.2 (4.5–9.2) | 0.13 | 7.4 (5.0–10.7) | 7.2 (5.1–10.1) | 0.22 |
Absolute eosinophil count | 100 (0–273) | 162 (0–367) | 0.02 | 82 (0–201) | 95 (0–233) | 0.21 |
Absolute Lymphocyte count | 1444 (924–2207) | 1848 (1050–2498) | < 0.01 | 1173 (770–1785) | 1728 (833–1985) | < 0.01 |
Hemoglobin | 13.0 (11.8–14.1) | 13.5 (12.3–14.3) | 0.01 | 12.6 (11.0–14.3) | 12.8 (11.3–14.1) | 0.15 |
Platelets | 252 (202–310) | 272 (232–325) | < 0.01 | 225 (172–287) | 226 (173–299) | 0.31 |
Viral testing (n) | 315 | 67 | 379 | 182 | ||
Viral positivity | 113 (36)* | 12 (18) | 0.02 | 98 (26) | 30 (16) | 0.03 |
Rhinovirus | 46 (41) | 2 (17) | 0.02 | 27 | 5 | 0.06 |