Fig. 2

Alluvial plot of changes in prevalence of different combinations of oxygenation and compliance over time from baseline to day 21, among patients who remained on controlled ventilation and had available data on oxygenation and compliance, in (A) the ARDSNet cohort, and (B) the CARDS cohort. Each block represents a different combination, and the height of a block represents the number of patients in this combination. Combinations at baseline are illustrated with different colors. Each stream field between two blocks represents the change in the number of patients in the respective combinations from baseline to day 21, and the height of a stream field is proportionate to this number of patients. A total of 108 and 94 patients with available data on oxygenation and compliance on both baseline and day 21 are included in the alluvial plot of the ARDSNet and CARDS cohort, respectively. MH-HiC: mild-moderate hypoxemia/high compliance; MH-LoC: mild-moderate hypoxemia/low compliance; SH-HiC: severe hypoxemia/high compliance; and SH-LoC: severe hypoxemia/low compliance