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Fig. 1 | Respiratory Research

Fig. 1

From: Fine particulate matter contributes to COPD-like pathophysiology: experimental evidence from rats exposed to diesel exhaust particles

Fig. 1

Study protocol and structural changes in different compartments of rat lung. The DEP generator and exposure chamber were shown in (A), while the schema of study protocol was demonstrated in (B). Total wall area (WAt) of large airways showing no significant difference following 2-wk, 4-wk and 8-wk DEP exposures, respectively, as compared to the filtered air controls (C-D). DEP exposures for three durations induced significant increases in WAt of small airways (E-F). Compared to the filtered air control, 4-wk and 8-wk DEP exposures, respectively, resulted in significant increases in MLI of alveoli (G-H). Data were expressed as mean (95% CI). ns = not significant, *** p < 0.001. n = 6 rats/group. Bars in all the HE staining images = 100 μm

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Respiratory Research

ISSN: 1465-993X

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