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Fig. 5 | Respiratory Research

Fig. 5

From: Genetic and observational associations of lung function with gastrointestinal tract diseases: pleiotropic and mendelian randomization analysis

Fig. 5

Relevant tissue and cell types for the pleiotropic results. The heritability enrichment for each trait pair was estimated using S-LDSC based on 220 tissue and cell-type specific histone marks. Only the 28 tissue and cell-type specific histone marks that had a P-value of less than 0.05/220 in at least one trait pair are presented. Notably, the heritability of a minimum of six trait pairs was found to be enriched in five specific markers, which are highlighted in red. The color and size of the circles indicate the enrichment at the tissue and cell-type specific histone mark. * indicates P < 0.05/220

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