Fig. 3
Manhattan plots for the results of pleiotropic analyses. (A) FEV1-GORD pleiotropic analysis and (B) FEV1/FVC-IBD pleiotropic analysis. The red dashed lines indicate the genome-wide significance level at P = 5 × 10− 8, and the black dashed lines indicate the suggestive significance level at P = 1 × 10− 6. The blue point indicates the locus was associated with lung function (P-values of the variants within the lead variant 500 kb were lower than 5\(\times\)10−8); orange indicates the locus was associated with GIT disease; purple indicates the locus was associated with both traits; red indicates the locus was associated with neither trait