Fig. 2From: Ambient atmospheric PM worsens mouse lung injury induced by influenza A virus through lysosomal dysfunctionLysosome dysfunction increases influenza virus entry. Confocal microscopy of influenza virus entry into A549 cells, which were transfected with a nontargeting control siRNA (NC) or a LAMP1- or LAMP2-specific siRNA for 48 h and then treated with vehicle, H1N1 virus, or H5N1 virus for 4 h. The graph in the lower panel indicates the percentage of NP-positive cells determined using ImageJ software from at least 1,000 cells. Scale bars, 50 μm. The data are shown as the mean and standard deviation values. *P < 0.05Back to article page