Fig. 4
From: An epithelial gene signature of trans-IL-6 signaling defines a subgroup of type 2-low asthma
Expression of the IL-6 + sIL-6Rα gene signature in asthma. The IL-6 + sIL-6Rα gene signature was investigated in asthma patients and controls to study enrichment. A Enrichment plot of the Gene signature in asthma patients vs. controls, including the profile of the running enrichment score, and positions of gene-set members on the rank-ordered list. B patients were ranked based on the expression of the gene signature and divided into four quantiles. The IL-6 + sIL-6Rα high and IL-6 + sIL-6Rα low quartiles were used to inform the analyses reported in Table 1