Fig. 2
From: An epithelial gene signature of trans-IL-6 signaling defines a subgroup of type 2-low asthma
Scatter plot of the Log2 foldchanges of the differential gene expression analyses. Six fully differentiated hAEC were stimulated by IL-6, IL-6 + sIL-6Rα, or left unstimulated (control). Differential gene expression analyses were conducted using RNA-seq data of each of the stimulated conditions and compared against the control. Log2 foldchanges of the significant differentially expressed genes of both IL-6 and IL-6 + sIL-6Rα are shown in the scatterplot and directly compared to each other. The colors indicate in which analysis the gene was significant (q < 0.05). The dotted line represents a hypothetical correlation of y = x. The orange line is the linear fit of all the significant genes showing a trend towards the y-axis (y = 1.2x − 0.00869). NS; non-stimulated, DEG; differentially expressed genes