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Fig. 5 | Respiratory Research

Fig. 5

From: METTL3-mediated m6A RNA methylation induces the differentiation of lung resident mesenchymal stem cells into myofibroblasts via the miR-21/PTEN pathway

Fig. 5

METTL3 is involved in TGF-β1-induced differentiation of LR-MSCs into myofibroblasts by targeting miR-21. A, B The mRNA and protein expression levels of myofibroblast markers (α-SMA, type I collagen, and Vimentin) in LR-MSCs with or without TGF-β1 treatment and miR-21 inhibitor. C, D The mRNA and protein expression levels of myofibroblast markers (α-SMA, type I collagen, and Vimentin) in LR-MSCs with or without METTL3 silencing, combined with or without treatment with TGF-β1 and miR-21 inhibitor. β-Actin was used as a reference gene. **P < 0.01

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Respiratory Research

ISSN: 1465-993X

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