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Table 1 Subjects’ clinical characteristics

From: S100A alarmins and thymic stromal lymphopoietin (TSLP) regulation in severe asthma following bronchial thermoplasty

 

Pre-BT

Post-BT

p-value

Number of subjects

20

20

 

Months since BT*

–

23 (15)

 

Age (years)†

47 ± 2

49 ± 2

 

Sex (M/F)

8/12

8/12

 

Smoking status (no/ex/yes)

13/6/1

13/6/1

 

Atopy (no/yes)

6/14

6/14

 

Inhaled corticosteroid dose (µg)†,§

1275 ± 175

938 ± 166

0.035

Median (range)

1375 (0–3000)

750 (0–3000)

 

Long acting β2-agonist (µg)†,ll

114 ± 14

102 ± 13

0.45

Median (range)

100 (0–250)

100 (0–200)

 

Oral corticosteroids (n)

4 (7.5–30.0)

3 (5.0–10.0)

0.25

Omalizumab (n)

3

3

> 0.99

Mepolizumab (n)

1

2

0.60

Montelukast (n)

9

8

> 0.99

Post-BD FEV1 (L)†

2.66 ± 0.18

2.83 ± 0.19

0.17

Count of severe exacerbations‡

1 (0–10)

0 (0–2)

0.019

ACSS†

71 ± 4

88 ± 3

0.0004

  1. *Mean (median)
  2. †Mean ± standard error
  3. ‡Median (range)
  4. §Fluticasone propionate or equivalent
  5. llSalmeterol or equivalent