Fig. 8
From: Keratin 15 protects against cigarette smoke-induced epithelial mesenchymal transformation by MMP-9
KRT15 knockdown promoted MMP-9 expression and EMT progression in vitro. A Western blot analysis of E-cadherin and Vimentin. B mRNA level of MMP-9 in HBE cells. C MMP-9 concentration in cellular supernatant. D Protein levels of E-cadherin and Vimentin. E Cell viability. *p < 0.05; **p < 0.01;***p < 0.001. NC negative control, NC CSE negative control + 1.5% CSE, shKRT15 HBE cells using an shRNA targeting KRT15, shKRT15 CSE HBE cells using an shRNA targeting KRT15 + 1.5%CSE, shKRT15 CSE-SB-3CT HBE cells using an shRNA targeting KRT15 + 1.5%CSE + SB-3CT