Fig. 7
From: Keratin 15 protects against cigarette smoke-induced epithelial mesenchymal transformation by MMP-9
CSE stimulated Krt15 mRNA expression and reduced cell viability. A stimulated with 0.5%, 1%, and 1.5% CSE for 48 h, B with 1.5% CSE for 24 and 48 h, C treated with or without shRNA targeting KRT15 in the presence or absence of CSE. D Viability of HBE cells treated with or without shRNA targeting KRT15 in the presence or absence of CSE. ***p < 0.001;****p < 0.0001. NC negative control, NC CSE negative control + 1.5% CSE, shKRT15 HBE cells using an shRNA targeting KRT15; shKRT15 CSE, HBE cells using an shRNA targeting KRT15 + 1.5%CSE