Fig. 3
From: Keratin 15 protects against cigarette smoke-induced epithelial mesenchymal transformation by MMP-9
Knockout of Krt15 aggravates CS-induced lung injury and inflammatory infiltration. A H&E staining, B lung injury score, C MAST, D DI, E MLI, F WBC number in BALF, and G IL-6 and IL-1β (H) concentration. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001. WT wild-type, WT CS wild-type + CS exposure, Krt15−/− Krt15 knockout mice, Krt15−/− CS Krt15 knockout mice + CS exposure, CS cigarette smoking. The arrows point to inducible bronchus-associated lymphoid tissue (iBALT)