Fig. 1

A) Unsupervised hierarchical clustering of 62 neonates with BPD demonstrated as a dendrogram. Agglomerative clustering with Euclidean distances and Ward’s linkage was used to create four endotypes up to the third-order branching patterns of the condition tree. B) Principal components analysis demonstrating spatial separation among the BPD endotypes based on 7,319 genes differentially expressed in BPD