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Fig. 1 | Respiratory Research

Fig. 1

From: The impact of SARS-CoV-2 infection in patients with cystic fibrosis undergoing CFTR channel modulators treatment: a literature review

Fig. 1

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) penetrates cells by binding between its peak protein (spike; S) to angiotensin-converting enzyme 2 (ACE-2). ACE-2 converts angiotensin (Ang)-II to Ang 1–7. The Ang1-7 has opposite biological actions to Ang-II (i.e., antifibrotic, antioxidant, antihypertrophic and vasodilatory effects) through stimulation of Mas receptor (MasR)

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Respiratory Research

ISSN: 1465-993X

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