Table 2 clinical characteristics of high-risk and low-risk groups in the training set
Characteristic | high risk, N = 1221 | low risk, N = 1241 | p-value2 | multivariate |
|---|---|---|---|---|
age | 62 (55, 67) | 61 (55, 67) | > 0.9 | |
gender | < 0.001 | |||
Female | 48 (39%) | 75 (60%) | ||
Male | 74 (61%) | 49 (40%) | ||
max diameter(mm) | 39 (28, 54) | 32 (22, 43) | < 0.001 | 0.008 |
smoking history | 57 (47%) | 32 (26%) | < 0.001 | |
lung cancer family history | 12 (9.8%) | 12 (9.7%) | > 0.9 | |
ProGRP | 42 (36, 54) | 44 (39, 58) | 0.11 | |
CEA | 4 (2, 7) | 3 (2, 5) | 0.2 | |
cyfra | 2.25 (1.70, 3.48) | 2.20 (1.68, 3.30) | 0.7 | |
NSE | 13.50 (12.60, 15.80) | 13.11 (12.10, 14.50) | 0.062 | |
SCCA | 0.80 (0.60, 1.00) | 0.70 (0.50, 0.90) | 0.2 | |
type | < 0.001 | < 0.001 (pure-GGO) | ||
CTR < 0.5 | 1 (0.8%) | 19 (15%) | ||
CTR > 0.5 | 1 (0.8%) | 5 (4.0%) | ||
pure-GGO | 0 (0%) | 14 (11%) | ||
solid | 120 (98%) | 86 (69%) | ||
lobular | 36 (30%) | 56 (45%) | 0.011 | 0.013 |
spiculation | 76 (62%) | 73 (59%) | 0.6 | |
pleural traction | 37 (30%) | 26 (21%) | 0.093 | |
air bronchus | 19 (16%) | 35 (28%) | 0.017 | 0.011 |
vessel | 39 (32%) | 65 (52%) | 0.001 | |
hollow | 17 (14%) | 16 (13%) | 0.8 | |
smooth edge | 9 (7.4%) | 4 (3.2%) | 0.15 | |
adjacent to pleural | 15 (12%) | 15 (12%) | > 0.9 |