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Table 3 Laboratory and imaging findings of patients with and without cough or sputum in PRO after 12 months

From: Cough and sputum in long COVID are associated with severe acute COVID-19: a Japanese cohort study

 

Cough

 

Sputum

 

Symptom (+)

(N = 32)

Symptom (-)

(N = 692)

p value

Symptom (+)

(N = 36)

Symptom (-)

(N = 688)

p value

Laboratory findings, median (IQR)

 WBC (cells/µl)

5070 (4125–7250)

4846 (3900–6200)

0.151a

5065 (4007-7457.5)

4840 (3900–6200)

0.121a

 %NEU

73.5 (64.7–84.1)

68.95 (60–77)

0.004a

72 (63.2–82.8)

69 (60–77)

0.012a

 %EOS

0 (0–1)

0 (0–1)

0.494a

0 (0–1)

0 (0–1)

0.099a

 %LYM

17 (9.75-25)

22.5 (15.8–30)

0.006a

19 (10.3–26)

22.75 (15.3–30)

0.056a

 Cre (mg/dl)

0.87 (0.65–1.08)

0.8 (0.65–0.97)

0.665a

0.86 (0.65-1.00)

0.81 (0.65–0.97)

0.947a

 LDH (IU/L)

293 (239–402)

229 (190–297)

< 0.001a

278 (204–329)

230 (191-294.5)

0.087a

 UA (mg/dl)

5 (4.05–5.85)

4.45 (3.575-5.5)

0.107a

5 (3.75–5.65)

4.5 (3.5–5.5)

0.245a

 ferritin (ng/ml)

423 (171.75–639.9)

314 (150-596.9)

0.172a

409 (232-616.85)

314.5 (148.75-3597.18)

0.786a

 KL-6 (U/ml)

304 (217–531)

220 (171–312)

0.022a

232 (177.75–336.5)

221.5 (172-318.75)

0.745a

 HbA1c (%)

6.4 (5.9–7.2)

5.9 (5.6–6.4)

0.031a

6.05 (5.7–6.85)

5.9 (5.6–6.4)

0.539a

 D-dimer (µg/ml)

0.9 (0.6–1.5)

0.8 (0.5–1.3)

0.576a

1.04 (0.7–1.55)

0.8 (0.5–1.3)

0.254a

Imaging examination n (%)

 Chest X-ray (GGO)

16 (50.0)

318 (46.0)

0.153b

22 (61.1)

312 (45.3)

0.179b

 Chest X-ray (infiltration)

6 (18.8)

124 (17.9)

0.314b

8 (22.2)

122 (17.7)

0.198b

 Chest X-ray ( ≧ 50% within 48 h)

2 (6.3)

49 (7.1)

0.848b

2 (6.3)

49 (71.2)

0.806b

 Chest CT (GGO)

28 (87.5)

429 (62.0)

0.004b

31 (86.1)

426 (61.9)

0.128b

 Chest CT (infiltration)

12 (37.5)

193 (27.9)

0.112b

13 (36.1)

192 (27.9)

0.169b

  1. Abbreviation: WBC, white blood cell; NEU, neutrophil; EOS, eosinophil; LYM, lymphocyte; LDH, lactate dehydrogenase; CT, computed tomography; GGO, ground-glass opacity, a t-test, b Chi-Square test.