Table 5 Changes in FVC at Week 48 by decile of predicted emphysema extent (clinical trial cohort)
From: A formula for predicting emphysema extent in combined idiopathic pulmonary fibrosis and emphysema
Decile of predicted emphysema extent | N | Median predicted emphysema extent, % | Mean (SD) FVC, L | Change in mean (SD) FVC from baseline | |
|---|---|---|---|---|---|
Relative, % | Absolute, L | ||||
Total | 455 | 8.4 | 2.80 (0.78) | –5.4 (12.1) | –0.14 (0.34) |
1st | 45 | –4.5 | 2.48 (0.68) | –5.7 (14.2) | –0.12 (0.32) |
2nd | 46 | 0.3 | 2.57 (0.69) | –5.5 (12.3) | –0.15 (0.32) |
3rd | 45 | 3.1 | 2.72 (0.81) | –8.8 (13.1) | –0.22 (0.34) |
4th | 46 | 5.3 | 2.65 (0.69) | –4.9 (11.5) | –0.15 (0.31) |
5th | 45 | 7.6 | 2.67 (0.50) | –7.0 (9.5) | –0.18 (0.23) |
6th | 46 | 9.2 | 2.76 (0.76) | –4.6 (12.8) | –0.12 (0.32) |
7th | 46 | 11.3 | 2.74 (0.71) | –6.2 (12.8) | –0.15 (0.68) |
8th | 45 | 13.4 | 3.03 (0.87) | –7.6 (9.6) | –0.23 (0.30) |
9th | 46 | 15.9 | 3.12 (0.90) | –2.6 (10.2) | –0.07 (0.34) |
10th | 45 | 21.0 | 3.21 (0.80) | –0.8 (12.7) | –0.02 (0.46) |