Table 1 Demographics and clinical characteristics for patient populations with IPF and emphysema
From: A formula for predicting emphysema extent in combined idiopathic pulmonary fibrosis and emphysema
Characteristic* | Development cohort (N = 76) | Clinical trial test cohort (N = 174) | Real-world test cohort (N = 110) |
|---|---|---|---|
Male sex, n (%) | 66 (86.8) | 146 (83.9) | 91 (82.7) |
Smoking status, n (%) | |||
Current | 14 (18.4)‡ | 22 (12.6) | 1 (0.9)§ |
Former | 58 (76.3)‡ | 98 (56.3) | 88 (80.0)§ |
Age, years | 62.3 (10.7) | 64.6 (8.6) | 69.7 (8.2) |
FVC, % predicted | 81.7 (21.1) | 75.9 (13.4) | 74.9 (18.2) |
FEV1, % predicted | 78.2 (18.6) | 76.0 (12.8) | 76.4 (15.9) |
Corrected DLco||, % predicted | 36.9 (14.4) | 41.1 (10.0) | 34.9 (13.8) |
CPI | 50.4 (14.2) | 49.9 (8.8) | 54.6 (12.3) |
Fibrosis extent, % | 49.3 (19.7) | 41.2 (13.9) | 27.9 (10.9) |
Isolated emphysema extent, % | 7.3 (6.1) | 6.8 (8.6) | 6.1 (8.6) |
Admixed emphysema extent, % | 11.0 (15.6) | 6.3 (7.0) | 5.5 (5.3) |
Total emphysema extent, % | 18.3 (17.3) | 13.1 (13.7) | 11.6 (12.2) |
CPFE Index | 17.9 (12.8) | 12.1 (6.9) | 13.8 (10.5) |