Hospitalisation patterns in interstitial lung diseases: data from the EXCITING-ILD registry

Respiratory Research

Table 3 Output of Cox regression model of time to first hospitalisation and time to first ILD-hospitalisation analysis by GAP Index (n=601) and ILD subtype (n=468)

	Time to first hospitalisation		Time to first ILD-hospitalisation
	HR [95% CI]	p value (Wald test)	HR [95% CI]	p value (Wald test)
GAP Index
II vs. I	2.5 [1.91, 3.27]	< 0.001	2.36 [1.67, 3.33]	< 0.001
III vs. I	2.99 [2.24, 3.99]	< 0.001	3.13 [2.2, 4.47]	< 0.001
No PFT vs. I	2.14 [1.36, 3.36]	< 0.001	2.34 [1.35, 4.05]	0.002
ILD Subtype
Granulomatous lung diseases vs. IPF	0.35 [0.25, 0.48]	< 0.001	0.23 [0.15, 0.36]	< 0.001
HP vs. IPF	0.82 [0.58, 1.18]	0.287	0.96 [0.64, 1.44]	0.844
CTD-ILD vs. IPF	1.59 [1.1, 2.3]	0.014	1.53 [0.99, 2.36]	0.055
Pneumoconiosis vs. IPF	0.68 [0.3, 1.54]	0.353	0.14 [0.02, 1.02]	0.052
Drug related ILD vs. IPF	0.97 [0.51, 1.85]	0.936	0.89 [0.41, 1.9]	0.758
Radiotherapy associated ILD vs. IPF	0.92 [0.34, 2.49]	0.873	0.34 [0.05, 2.44]	0.283
CPFE vs. IPF	1.29 [0.7, 2.38]	0.412	0.97 [0.43, 2.2]	0.936

For these analyses, Hazard Ratios were drawn from a comparison of the most relevant ILD subtypes and IPF. HR= Hazard Ratio, CI= confidence interval, No PFT= No pulmonary function testing, IPF= Idiopathic pulmonary fibrosis, HP= Hypersensitivity pneumonitis, CTD-ILD= Rheumatic and connective tissue diseases with pulmonary involvement, CPFE= Fibrosis in emphysema patients without signs of other ILDs

ISSN: 1465-993X