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Fig. 5 | Respiratory Research

Fig. 5

From: Proteomic biomarkers for survival in systemic sclerosis-associated pulmonary hypertension

Fig. 5

The protein–protein interaction network obtained using String software. In order to highlight the different links between the 7 significantly identified proteins, we performed an enrichment by adding “intermediate proteins” that link identified factors. Proteins of interest are underlined in green. A The protein-protein interaction network for the 7 identified significant proteins after enrichment by adding “intermediate connecting proteins”. B The protein-protein interaction network for the 2 identified significant proteins increased in long surviving patients compared to short surviving patients after enrichment by adding intermediate proteins C. The protein-protein interaction network for the 5 identified significant proteins increased in short surviving patients compared to long surviving patients after enrichment by adding intermediate proteins. ADAMTS13 A disintegrin and metalloproteinase with thrombospondin motifs 13, SERPIND1 Heparin cofactor 2, FBN1 Fibrillin-1, OLFM1 Noelin, IGFBP7 insulin-like growth factor-binding protein 7, PTGDS glutathione-independent PGD synthase, C7 complement component C7, F2 prothombin, C5 complement C5, VWF Von Willebrand factor, C6 complement component C6, ELN elastine, FGG fibrinogen gamma chain, FGA fibrinogen alpha chain, FGB fibrinogen beta chain, MFAP2 microfibrillar-associated protein, INS insulin

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