From: Spatially distinct molecular patterns of gene expression in idiopathic pulmonary fibrosis
Demographics | Controls with histologically normal lung tissue (N = 12) | IPF (N = 32) |
---|---|---|
Sex | Â | Â |
 Male | 7 (58) | 22 (69) |
 Female | 5 (42) | 10 (31) |
Age | Â | Â |
 Min | 28 | 36 |
 Median | 64.5 | 65 |
 Max | 74 | 78 |
 Mean (SD) | 60.00 (12.88) | 61.91 (8.89) |
Smoker | Â | Â |
 Yes | 9 (75) | 21 (66) |
 No | 3 (25) | 11 (34) |
Race | Â | Â |
 White | 11 (92) | 28 (88) |
 Black | 0 (0) | 3 (9) |
 Asian | 1 (8) | 0 (0) |
 Unknown | 0 (0) | 1 (3) |
Ethnicity | Â | Â |
 Non-Hispanic | 12 (100) | 30 (94) |
 Hispanic | 0 (0) | 1 (3) |
 Unknown | 0 (0) | 1 (3) |
Comorbidities | Â | Â |
 Angina | 1 (8) | 5 (16) |
 Heart failure | 0 (0) | 1 (3) |
 Arrhythmia | 2 (17) | 5 (16) |
 Hyperlipidemia | 3 (25) | 13 (41) |
 Diabetes | 3 (25) | 6 (19) |
 Lung cancer | 2 (17) | 0 (0) |
 Other cancer | 4 (33) | 2 (6) |
 Rheumatoid arthritis | 0 (0) | 2 (6) |
 Gerd | 4 (33) | 11 (34) |
 Asthma | 0 (0) | 1 (3) |
 Pulmonary hypertension | 1 (8) | 0 (0) |
 Emphysema | 2 (17) | 3 (9) |
rs35705950 genotype | Â | Â |
 GG | 5 (42) | 13 (41) |
 GT | 6 (50) | 16 (50) |
 TT | 1 (8) | 3 (9) |
 Summary of ROIs | # regions (# subj) | # regions (# subj) |
 Normal lung parenchyma | 25 (12) | 33 (27) |
 Normal bronchiolar epithelium | 10 (10) | 22 (22) |
 Transition |  | 59 (32) |
 Dense fibrosis |  | 58 (32) |
 Honeycomb metaplasia |  | 24 (19) |