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Table 1 Summary of subject demographics information

From: Spatially distinct molecular patterns of gene expression in idiopathic pulmonary fibrosis

Demographics

Controls with histologically normal lung tissue

(N = 12)

IPF

(N = 32)

Sex

  

 Male

7 (58)

22 (69)

 Female

5 (42)

10 (31)

Age

  

 Min

28

36

 Median

64.5

65

 Max

74

78

 Mean (SD)

60.00 (12.88)

61.91 (8.89)

Smoker

  

 Yes

9 (75)

21 (66)

 No

3 (25)

11 (34)

Race

  

 White

11 (92)

28 (88)

 Black

0 (0)

3 (9)

 Asian

1 (8)

0 (0)

 Unknown

0 (0)

1 (3)

Ethnicity

  

 Non-Hispanic

12 (100)

30 (94)

 Hispanic

0 (0)

1 (3)

 Unknown

0 (0)

1 (3)

Comorbidities

  

 Angina

1 (8)

5 (16)

 Heart failure

0 (0)

1 (3)

 Arrhythmia

2 (17)

5 (16)

 Hyperlipidemia

3 (25)

13 (41)

 Diabetes

3 (25)

6 (19)

 Lung cancer

2 (17)

0 (0)

 Other cancer

4 (33)

2 (6)

 Rheumatoid arthritis

0 (0)

2 (6)

 Gerd

4 (33)

11 (34)

 Asthma

0 (0)

1 (3)

 Pulmonary hypertension

1 (8)

0 (0)

 Emphysema

2 (17)

3 (9)

rs35705950 genotype

  

 GG

5 (42)

13 (41)

 GT

6 (50)

16 (50)

 TT

1 (8)

3 (9)

 Summary of ROIs

# regions

(# subj)

# regions

(# subj)

 Normal lung parenchyma

25 (12)

33 (27)

 Normal bronchiolar epithelium

10 (10)

22 (22)

 Transition

 

59 (32)

 Dense fibrosis

 

58 (32)

 Honeycomb metaplasia

 

24 (19)