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Fig. 1 | Respiratory Research

Fig. 1

From: [18 F] -FAPI-42 PET/CT assessment of Progressive right ventricle fibrosis under pressure overload

Fig. 1

Structural and functional disorders of the right ventricle under pressure overload. (A) Study schema for PAB model. (B)-(D) Right heart catheterization suggests increased RVSP, mRAP and RVEDP. (E) Ratio of the heart weight to body weight. (F-I) Echocardiography indicates enlarged right ventricular (RV) cavity and impaired RV contractility in PAB rats (n = 5–7/group). ns = not significant, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, compared with sham group. # p < 0.05, ## p < 0.01, ### p < 0.001, compared with the indicated time point in PAB group. RVSP = right ventricular systolic pressure, mRAP = mean right atrial pressure, RVEDP = right ventricular end-diastolic pressure, HW/BW = heart weight/ body weight, RVCO = right ventricular cardiac output, TAPSE = tricuspid annular plane systolic excursion, RVEDA = right ventricular end-diastolic area, RVESA = right ventricular end-systolic area, PAB = pulmonary artery banding group, sham = sham group

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