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Table 2 Factorial ANCOVA analysis

From: COVID-19 induces more pronounced extracellular matrix deposition than other causes of ARDS

 

COVID-19

Sex

Interaction*

MV duration

Age

BMI

PaO2/FiO2 ratio

Collagen

F(1,38)

23.7

9.24

3.29

0.32

1.58

1.89

0.65

p-value

< 0.0001

0.004

0.077

0.572

0.216

0.177

0.425

partial η2

0.385

0.196

0.08

0.008

0.040

0.048

0.017

Elastic Fibres

F(1,37)

1.25

1.88

0.18

7.14

0.09

1.30

1.263

p-value

0.271

0.179

0.677

0.011

0.758

0.261

0.268

partial η2

0.033

0.048

0.005

0.162

0.003

0.034

0.033

Fibronectin

F(1,36)

18.94

0.822

0.69

0.387

0.475

0.50

0.759

p-value

< 0.0001

0.371

0.409

0.538

0.495

0.484

0.389

partial η2

0.345

0.022

0.019

0.011

0.013

0.014

0.021

Versican

F(1,37)

6.87

2.61

0.007

0.10

0.001

1.99

0.947

p-value

0.013

0.114

0.935

0.754

0.981

0.167

0.337

partial η2

0.157

0.066

0

0.003

0

0.051

0.025

TGF-β

F(1,37)

6.09

0.065

0.683

4.37

0.048

0.884

0.291

p-value

0.018

0.80

0.414

0.044

0.828

0.353

0.593

partial η2

0.141

0.002

0.018

0.106

0.001

0.023

0.008

Decorin

F(1,38)

5.25

3.99

0.025

0.73

0.97

0.189

0.596

p-value

0.028

0.053

0.875

0.399

0.329

0.666

0.445

partial η2

0.124

0.097

0.001

0.019

0.026

0.005

0.016

  1. * Interaction between the factors COVID-19 and sex. F (df, df error). Partial η2 = partial eta squared are measures of effect size; it represents the proportion of variance in the dependent variable associated with an effect. MV: Mechanical Ventilation. We observed no significant correlation among the covariates