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Table 1 Baseline characteristics of the eligible (before-match) and matched cohorts of adult close contacts of COVID-19 who received 2-dose and 3-dose vaccine

From: Effectiveness of the booster dose of inactivated COVID-19 vaccine against Omicron BA.5 infection: a matched cohort study of adult close contacts

Characteristics

Eligible cohorts

Matched cohorts

2 doses, n (column %)

3 doses, n (column %)

SMD

2 doses, n (column %)

3 doses, n (column %)

SMD

Total

3433 (100%)

33,666 (100%)

NA

3317 (100%)

16,051 (100%)

NA

Sex

 Male

1571 (45.8%)

16,061 (47.7%)

0.039

1555 (46.9%)

7388 (46.0%)

0.017

 Female

1862 (54.2%)

17,605 (52.3%)

1762 (53.1%)

8663 (54.0%)

Age group

 Young adult: 18–39 yr

1868 (54.4%)

16,241 (48.2%)

0.483

1868 (56.3%)

9313 (58.0%)

0.071

 Middle-age adult: 40–59 yr

851 (24.8%)

14,665 (43.6%)

851 (25.7%)

4271 (26.6%)

 Old-age adult: 60+ yr

714 (20.8%)

2760 (8.2%)

598 (18.0%)

2467 (15.4%)

Median age, yr [IQR]

37.0 [28.0, 55.0]

40.0 [31.0, 51.0]

0.074

36.0 [28.0, 53.0]

36.0 [28.0, 51.0]

0.070

Epidemiological week of 2022

 wk 31: Jul 31–Aug 6

775 (22.6%)

7230 (21.5%)

0.077

749 (22.6%)

3644 (22.7%)

0.047

 wk 32: Aug 7–Aug 13

1683 (49.0%)

17,510 (52.0%)

1670 (50.3%)

8261 (51.5%)

 wk 33: Aug 14–Aug 20

470 (13.7%)

3992 (11.9%)

406 (12.2%)

1970 (12.3%)

 wk 34: Aug 21–Aug 27

306 (8.9%)

2835 (8.4%)

293 (8.8%)

1236 (7.7%)

 wk 35: Aug 28–Sep 3

127 (3.7%)

1257 (3.7%)

127 (3.8%)

562 (3.5%)

 wk 36: Sep 4–Sep 10

72 (2.1%)

842 (2.5%)

72 (2.2%)

378 (2.4%)

Contact setting

 Household

101 (2.9%)

874 (2.6%)

0.069

94 (2.8%)

373 (2.3%)

0.036

 Community

131 (3.8%)

1198 (3.6%)

119 (3.6%)

551 (3.4%)

 Workplace

94 (2.7%)

1317 (3.9%)

94 (2.8%)

497 (3.1%)

 Unknown settings

3107 (90.5%)

30,277 (89.9%)

3010 (90.7%)

14,630 (91.1%)

Age group of source case

 Minor: < 18 yr

230 (6.7%)

1784 (5.3%)

0.107

210 (6.3%)

871 (5.4%)

0.070

 Young adult: 18–39 yr

1428 (41.6%)

15,193 (45.1%)

1428 (43.1%)

7223 (45.0%)

 Middle-age adult: 40–59 yr

1511 (44.0%)

14,733 (43.8%)

1469 (44.3%)

6995 (43.6%)

 Old-age adult: 60+ yr

264 (7.7%)

1956 (5.8%)

210 (6.3%)

962 (6.0%)

Vaccine status of source case

 0–1 dose

267 (7.8%)

2473 (7.3%)

0.054

261 (7.9%)

1130 (7.0%)

0.051

 2 doses

457 (13.3%)

3928 (11.7%)

407 (12.3%)

1881 (11.7%)

 3 doses

2709 (78.9%)

27,265 (81.0%)

2649 (79.9%)

13,040 (81.2%)