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Fig. 5 | Respiratory Research

Fig. 5

From: Rhinovirus infection induces secretion of endothelin-1 from airway epithelial cells in both in vitro and in vivo models

Fig. 5

In mouse models of AAD, RV increased ET-1 concentration in BALF, correlating with AHR. In OVA-induced A or HDM-induced B model of AAD, RV infection increased ET-1 secretion in BALF collected at 24 hpi. *p < 0.05 vs OVA or HDM alone, ***p < 0.001 vs PBS + Mock; Mean ± SEM, n = 6 (A) and n = 12–15 (B). ET-1 concentration in BALF was correlated with AHR (C), n = 7–10 mice

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