Fig. 2From: Rhinovirus infection induces secretion of endothelin-1 from airway epithelial cells in both in vitro and in vivo modelsPoly(I:C), a TLR3 agonist, induces ET-1 production. Poly(I:C) induced EDN1 expression A and ET-1 secretion B in a dose-dependent manner. ***p < 0.001 vs vehicle control, ##p < 0.01 vs 3 μg/ml. Each data point represents the mean of duplicate transwells of differentiated HBE cells from each donor (mean ± SD, n = 5 distinct donors)Back to article page