Fig. 1From: Rhinovirus infection induces secretion of endothelin-1 from airway epithelial cells in both in vitro and in vivo modelsRhinovirus infection induces ET-1 production. RV-A16 infection increased RV RNA in a dose-dependent manner (A–C). *p < 0.05, **p < 0.01, ***p < 0.001 vs 4 h, #p < 0.05, ##p < 0.01 vs 24 h. RV-A16 infection induced EDN1 expression (D–F, *p < 0.05 and **p < 0.01 vs 4 h, #p < 0.05 vs 24 h) and ET-1 secretion (G, **p < 0.001 vs 0 MOI, #p < 0.05 vs 0.1 MOI) in a dose-dependent manner. Each data point represents the mean of duplicate transwells of differentiated HBE cells from each donor (mean ± SD, n = 3 distinct donors)Back to article page