Fig. 3
From: Apoptosis inhibitor of macrophage (AIM)/CD5L is involved in the pathogenesis of COPD
Emphysema formation and cell death in PPE-treated mice. (A) Representative photomicrographs of lungs of the AIM−/− or WT mice on day 21 after PPE or vehicle treatment. Scale bar: 500 μm. (B) Quantification of MLI on day 21 after PPE or vehicle treatment. (C) Representative photomicrographs of TUNEL and Hoechst staining of lungs of the AIM−/− or WT mice on day 21 after PPE or vehicle treatment. Scale bar: 100 μm. (D) Quantification of TUNEL-positive cells on day 21 after PPE or vehicle treatment. Data are expressed as mean ± SEM (n = 3–6). *p < 0.05, ****p < 0.001 by the Welch’s t test with a Holm adjustment for (B) and the Tukey–Kramer test for (D)