Table 3 Future issues
From: Eosinophil extracellular traps in asthma: implications for pathogenesis and therapy
1. | How is EETosis initiated? |
2. | What is the mechanism of vital EETosis? |
3. | Improvement in various types of asthma with rhDNase treatment |
4. | The role of EETs in viral-induced asthma exacerbations |
5. | It is unclear whether the formation of EETs in asthma is regulated by other cells or molecules. Understanding these regulatory mechanisms could help us better understand the process of asthma exacerbations and provide targets for the development of new therapeutic approaches. |
6. | The distribution of EETs in patients with asthma is not fully understood. Further studies may reveal how it varies by type and severity of asthma and how it relates to asthma symptoms and response to treatment. |
7. | The potential role of EETs in the treatment of asthma requires further investigation. Some studies suggest that inhibition of EETs formation and function may be beneficial in reducing asthma symptoms and ameliorating inflammation. However, no specific therapeutic strategy targeting EETs has been widely adopted. |