Fig. 3
From: Eosinophil extracellular traps in asthma: implications for pathogenesis and therapy
Therapeutic potential drugs targeting a step in the release and formation of EETs. Many stimuli can induce eosinophil activation and the release of EETs, so therapeutic strategies for EETs need to be evaluated and selected on an individual basis. E.coli: Escherichia coli; RSV: Respiratory Syncytial Virus; PMA: Phorbol 12-myristate 13-acetate; LPS: lipopolysaccharide; C5a: Complement factor 5a; Ig: Immunoglobulin; TSLP: Thymic stromal lymphopoietin; IL-5: Interleukin 5; NADPH: Nicotinamide adenine dinucleotide phosphate; PAD4: Peptidyl arginine deaminase 4; ROS: Reactive oxygen species; DNaseI: Deoxyribonuclease I; CLCs: Charcot-Leyden crystals