From: Characterizing the urinary proteome of prematurity-associated lung disease in school-aged children
Variable | Term born (\(\ge\)37/40) n = 46 | Preterm born (\(\le\)34/40) n = 160 | Preterm born Controls n = 112 | pPRISm n = 27 | POLD n = 21 |
---|---|---|---|---|---|
Sex (male), n(%) | 23 (50.0) | 76 (47.5) | 52 (46.4) | 17 (63) | 7 (33.3) |
Ethnicity (white), n(%) | 45 (97.8) | 152 (95) | 105 (93.8) | 27 (100) | 20 (95.2) |
Age at testing (years), mean (SD) | 9.9 (1.1) | 10.4 (1.4)* | 10.4 (1.3) | 10.6 (1.6) | 10.1 (1.7) |
Weight (kg), mean (SD) | 36.3 (10.3) | 35.9 (9.7) | 36.4 (9.5) | 35.5 (9.1) | 33.9 (11.8) |
Body Mass Index (kg/m2), mean (SD) | 18.1 (3.2) | 17.5 (3.1) | 17.7 (3.0) | 17.0 (2.9) | 17.0 (3.9) |
Wheeze-ever, n(%) | 12 (26.1) | 97 (56.9)*** | 64 (57.1) | 15 (55.6) | 18 (85.7)†# |
Doctor-diagnosed asthma, n(%) | 2 (4.3) | 39 (24.4)** | 21 (18.8) | 7 (25.9) | 11 (52.4)††|
Neonatal Characteristics | |||||
Gestational age (weeks), mean (SD) | 40.1 (1.2) | 30.5 (2.8)*** | 30.4 (2.9) | 30.9 (2.9) | 30.2 (2.5) |
Birthweight (g), mean (SD) | 3499 (576) | 1549 (594)*** | 1577 (607) | 1587 (543) | 1352 (572) |
Birthweight (z-score), mean (SD) | 0.1 (0.99) | 0.11 (1.37) | 0.3 (1.42) | -0.12 (0.9) | -0.45 (1.46) |
Intrauterine growth restriction, n(%) | 3 (6.5) | 25 (15.6) | 15 (13.4) | 2 (7.4) | 8 (38.1)††## |
Antenatal Steroids, n(%) | 0 (0) | 137 (85.6)*** | 99 (88.4) | 22 (81.5) | 16 (76.2) |
Mechanical ventilation, n(%) | 0 (0) | 70 (43.8)*** | 53 (47.3) | 7 (25.9) | 10 (47.6) |
Bronchopulmonary Dysplasia (BPD), n(%) | 0 (0) | 47 (29.2)*** | 34 (30.4) | 7 (25.9) | 6 (28.6) |
Antenatal smoking, n(%) | 3 (6.5) | 22 (13.8) | 16 (14.3) | 4 (14.8) | 2 (9.5) |