Fig. 2

Evaluation of Anc80.AC effect on cardiopulmonary hemodynamic parameters and right ventricular function in rats 8 weeks post-PAH induction. Right ventricular (RV) hemodynamic parameters improved post gene therapy with Anc.80AC in PH model. A The mean pulmonary arterial pressure (mPAP, mm Hg). B Pulmonary vascular resistance index (PVR, dynes/sec/cmx5). C Right ventricular ejection fraction (RVEF, %). D Right ventricular mass (RV mass, mg). All continuous data were checked for normality and are presented as mean ± SD. Each group included 8 rats. Not significant p > 0.05; *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; ****p ≤ 0.0001