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Fig. 6 | Respiratory Research

Fig. 6

From: AMPK activation improves recovery from pneumonia-induced lung injury via reduction of er-stress and apoptosis in alveolar epithelial cells

Fig. 6

Metformin and Tideglusib decrease of ER-stress marker CHOP in AECs of PAK-infected mice. (a) Representative images and (b) fluorescence intensity scattergrams showed patterns of CHOP (red) accumulation, T-1α AECs (Type 1) fluorescence (green) and nuclei (blue) in lung sections from control and mice exposed to PAK alone for 24, 48, 72 and 96 h. Mice received metformin or Tideglusib 24 h post PAK-induced lung injury. Scattergrams indicate correlation of T-1α/CHOP fluorescence intensity (A.U.; arbitrary units)

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Respiratory Research

ISSN: 1465-993X

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