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Fig. 1 | Respiratory Research

Fig. 1

From: AMPK activation improves recovery from pneumonia-induced lung injury via reduction of er-stress and apoptosis in alveolar epithelial cells

Fig. 1

AMPK activation improved recovery from lung injury in mice subjected to P. aeruginosa infection. (a) Representative images depicted lung sections (H&E) from control and groups of mice exposed to PAK for 0 (control), 24, 28, 72 and 96 h. Dashed boxes are enlarged and depicted below. Arrows indicate infiltrates and accumulation of cellular debris in alveolar space. (b) The lung injury score from indicated groups of mice. (c) Therapeutic interventions with metformin and Tideglusib initiated during established lung injury, i.e., 24 h after exposure mice to PAK. (d-e) Lung sections (H&E) and (f) the lung injury score for indicated groups of mice. Data presented as Box plots, n = 5 mice/group. *P < 0.05 (ANOVA)

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Respiratory Research

ISSN: 1465-993X

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