Fig. 2

Venn diagram showing the overlap between clinical phenotypes of uncontrolled asthma, asthma exacerbations and severe asthma in 6424 children aged 2–17 years with actively treated asthma. Note that the diagram only includes the subpopulation of children fulfilling at least one of the criteria above. Uncontrolled asthma was defined as > 400 annual doses of SABA for ages 0–11, > 600 for ages 12 and above, asthma exacerbations was defined as redemption of either 37.5 mg prednisolone for 5 days or hospital admission with asthma. Severe asthma was defined as GINA Step 3 + 4 treated asthma with two moderate or one severe/near-fatal exacerbation(s) for ages 0–11, GINA Step 4 treated asthma with two moderate or one severe/near-fatal exacerbation(s) or GINA Step 5 regardless of exacerbations for ages 12 and above