Table 2 Association between genetic variations in XDH gene and risk of development of sepsis among 353 African American sepsis patients (with and without ARDS) and 406 control subjects
From: Xanthine oxidoreductase gene polymorphisms are associated with high risk of sepsis and organ failure
Marker | Chr.2 Position (hg19) | Function | Alleles | MAF (case/control) | OR (95% CI) | Pcrude | Padj* |
|---|---|---|---|---|---|---|---|
rs206805 | 31,630,867 | intron 1 |  A/G | 0.214/0.274 | 0.761 (0.579–0.999) | 0.014 | 0.049 |
rs513311 | 31,625,610 | intron 3 |  A/C | 0.076/0.125 | 0.609 (0.409–0.906) | 0.004 | 0.014 |
rs185925 | 31,609,993 | intron 8 |  C/T | 0.297/0.23 | 1.464 (1.107–1.936) | 0.004 | 0.005 |
rs561525 | 31,608,855 | intron 9 |  C/T | 0.057/0.099 | 0.552 (0.351–0.869) | 0.005 | 0.010 |
rs2163059 | 31,603,134 | intron 12 |  A/G | 0.479/0.412 | 1.35 (1.057–1.724) | 0.010 | 0.016 |
rs13387204 | 31,589,654 | intron (boundary) | C/T | 0.297/0.354 | 0.759 (0.591–0.975) | 0.027 | 0.031 |