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Fig. 8 | Respiratory Research

Fig. 8

From: CircItgb5 promotes synthetic phenotype of pulmonary artery smooth muscle cells via interacting with miR-96-5p and Uba1 in monocrotaline-induced pulmonary arterial hypertension

Fig. 8

CircItgb5 promotes synthetic phenotype of PASMCs by interacting with miR-96-5p and Uba1. A, C Protein expression of COL1A1 and SM22α was determined after the corresponding treatment. *0.01 ≤ P ≤ 0.05 versus (Lsh-NC + iCon), **0.001 ≤ P ≤ 0.009 versus (Lsh-NC + vector), #0.01 ≤ P ≤ 0.05 versus (Lsh-circItgb5 + iCon) or (Lsh-circItgb5 + vector), ##0.001 ≤ P ≤ 0.009 versus (Lsh-circItgb5 + vector). B, D The cell cycle of PASMCs was measured by flow cytometry. *0.01 ≤ P ≤ 0.05 versus (Lsh-NC + iCon), **0.001 ≤ P ≤ 0.009 versus (Lsh-NC + vector), #0.01 ≤ P ≤ 0.05 versus (Lsh-circItgb5 + iCon) or (Lsh-circItgb5 + vector). All data are presented as means ± SD (n = 3 biological replicates)

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Respiratory Research

ISSN: 1465-993X

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