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Table 2 Association of air pollution (pre-diagnosis exposure) with the severity of SSc-associated ILD at diagnosis (extensive ILD)

From: The association between air pollution and the severity at diagnosis and progression of systemic sclerosis-associated interstitial lung disease: results from the retrospective ScleroPol study

 

OR

p value

NO2

0.95 (0.91–1.00)

0.08

O3

1.12 (1.05–1.21)

0.002

PM10

0.91 (0.75–1.11)

0.36

PM2.5

0.87 (0.64–1.20)

0.39

  1. Logistic regression models adjusted for birth in Europe, tobacco smoking, anti-topoisomerase I antibodies positivity, usual interstitial pneumonia pattern, time between first non-Raynaud symptom and ILD diagnosis, and year of ILD diagnosis
  2. ILD: interstitial lung disease; NO2: nitrogen dioxide; O3: ozone; PM10 and PM2.5: particles with a 50% cutoff aerodynamic diameter of 10 µm and 2.5 µm, respectively