Fig. 1

Changes in clinical parameters of patients pre- and post-exercise. 6 min walking distance (C), oxygen consumption at peak exercise (E), peak VO2/pulse (F); CAT score of common symptoms: CAT score (K) and nocturnal oxygen saturation (L) are significantly changed; FVC (A & B), oxygen uptake anaerobic threshold (G), working load at peak exercise (D), cardiac function by CPET: oxygen pulse (J), resting and peak heart rate (H & I) are not changed significantly. FEV1 forced expiratory volume during the first second, FVC forced vital capacity, VO2 oxygen consumption, HR heart rate, SPO2 oxygen saturation, @AT at anaerobic threshold, “pre-” & “post” means pre- or post-12 weeks exercises in hospital