Skip to main content

Table 1 Clinical characteristics and perioperative data of normal oxygenation group, simple hypoxemia group, and ARDS group after surgery

From: Effect of pre-operative hypoxemia on the occurrence and outcomes of post-operative ARDS in Stanford type a aortic dissection patients

Variable

All patients

Normal oxygenation

Simple hypoxemia

ARDS

P-value

(n = 212)

(n = 51, 24.1%)

(n = 98, 46.2%)

(n = 63, 29.7%)

Age (year, M [IQR])

53.0 (44.3–62.0)

53.0 (41.0–59.0)

51.0 (44.0–62.0)

55.0 (46.0–66.0)

0.238

Male (n, %)

149 (70.3)

36 (70.6)

72 (73.5)

41 (65.1)

0.523

BMI (kg/m2,‾x±s)

26.4±4.1

24.5±3.8

27.0±3.9

27.1±4.1

0.001a

Smoking (n, %)

78 (36.8)

20 (39.2)

32 (32.7)

26(41.3)

0.498

Drinking (n, %)

59 (27.8)

17 (33.3)

24 (24.5)

18 (28.6)

0.514

Hypertension (n, %)

163 (76.9)

28 (54.9)

74 (75.5)

61 (96.8)

< 0.001b

Diabetes (n, %)

10 (4.7)

1 (2.0)

4 (4.1)

5 (7.9)

0.310

CHD (n, %)

31 (14.6)

7 (14.3)

14 (14.3)

10 (15.9)

0.941

Stroke (n, %)

15 (7.1)

5 (9.8)

5 (5.1)

5 (7.9)

0.443

CKD (n, %)

6 (2.8)

1 (2.0)

2 (2.0)

3 (4.8)

0.574

Onset to operation time (h, M [IQR])

19.0 (11.0-53.8)

25.0 (13.0-144.0)

20

(10.0-72.8)

16

(9.0–27.0)

0.027c

Hypoxemia (n, %)

76 (35.8)

6 (11.8)

40 (40.8)

30 (47.6)

< 0.001d

Shock (n, %)

9 (4.2)

1 (2.0)

3 (3.1)

5 (7.9)

0.275

WBC (109/L, M [IQR])

11.7

(8.7–15.1)

9.5

(7.8–13.1)

12.3 (9.10–15.1)

11.8

(8.8–15.8)

0.009e

NLR (M [IQR])

0.11 (0.07–0.20)

0.12 (0.07–0.30)

0.10 (0.07–0.19)

0.10 (0.07–0.20)

0.331

PLT (109/L, M [IQR])

176.0 (145.0-215.8)

175.0 (144–218)

182.0 (149.8-215.3)

172.0 (139.0-221.0)

0.720

Hemoglobin (g/L,‾x±s)

132.7 ± 18.5

129.7 ± 17.8

133.5 ± 18.8

134.1 ± 18.6

0.391

PT (s, M [IQR])

12.5 (11.8–13.6)

12.7 (12.2–13.9)

12.4 (11.8–13.5)

12.6 (11.6–13.4)

0.178

Fibrinogen (g/L, M [IQR])

2.2 (1.8-3.0)

2.5 (1.8–3.3)

2.2 (1.8-3.0)

2.2 (1.9–2.8)

0.553

ALT (U/L, M [IQR])

27.0 (20.0-38.8)

24.0 (18.0-34.3)

27.0 (21.75-41)

27.0 (18.1–46.0)

0.106

Bilirubin (µmol/L, M [IQR])

15.7 (12.0-22.3)

15.2 (11.3–22.3)

15.7 (12.7–21.1)

15.7 (10.6–22.8)

0.562

Surgical method

Total arch replacement (n, %)

Hemiarch replacement (n, %)

201(94.8)

11(5.2)

44(86.3)

7(13.7)

94(95.9)

4(4.1)

63(100)

0(0)

0.002f

Creatinine (µmol/L, M [IQR])

73.6 (62.5–90.7)

69.2 (56.3–86.1)

72.6 (62.9–90.7)

78.9 (65.6-100.8)

0.100

Operation time (min, M [IQR])

360.0 (312.8-439.3)

355.0 (300.0-420.0)

354 (309.8-418.5)

385.0 (340.0-530.0)

0.002 g

CBP time (min, M [IQR])

180.7 (156.2–221.0)

183.0 (147.0-219.8)

174.2 (156.9-218.8)

184.9 (159.0-240.0)

0.306

ACCT (min, M [IQR])

103.5 (83.1-127.4)

106.0

(91–140)

105.2 (81.7-127.1)

100.0 (80.0-124.0)

0.313

Central body temperatu(℃,M[IQR])

28.9

(28.3–29.6)

29.3

(28.4–29.7)

28.9

(28.2–29.6)

2 8.8

(28.4–29.5)

0.208

Perioperative blood loss (mL, M [IQR])

2448.0 (1877.8–3441.0)

2065.0 (1711.0-2850.0)

2252.5 (1845.8-3081.8)

2878.0 (2166.0-5303.0)

< 0.001 h

Perioperative transfusion (RBC, U, M [IQR])

6.0 (4.0–10.0)

6.0 (2.0–8.0)

6.0 (3.8–8.5)

8.0 (6.0–14.0)

0.002i

Perioperative transfusion (plasma, mL, M [IQR])

1000.0 (800.0-1400.0)

800.0 (600.0-1200.0)

1000.0 (800–1305.0)

1150.0 (800.0-1800.0)

< 0.001j

Perioperative fluid load(ml, M [IQR])

-849.5(-1709.5-511.3)

-712.0(-1535.0-427.0)

-1010.0(-1933.0-272.8)

-1400.0(-1829.0-1287.0)

0.168

  1. PT: prothrombin time ; BMI: body mass index; IQR: interquartile range; CHD: coronary heart disease; CKD: chronic kidney disease; WBC: white blood cell; NLR: neutrophil–lymphocyte ratio; PLT: platelet count; CPB: cardiopulmonary bypass; ACCT: aortic cross clamp time; RBC: red blood cell.
  2. a: ARDS vs. normal oxygenation (P = 0.001), normal oxygenation vs. simple hypoxemia (P < 0.001); b: ARDS vs. normal oxygenation (P < 0.001), ARDS vs. simple hypoxemia (P < 0.001), normal oxygenation vs. simple hypoxemia (P = 0.01);
  3. c: ARDS vs. normal oxygenation (P = 0.022);
  4. d: ARDS vs. normal oxygenation (P < 0.001), normal oxygenation vs. simple hypoxemia (P < 0.001);
  5. e: ARDS vs. normal oxygenation (P = 0.023), normal oxygenation vs. simple hypoxemia (P = 0.014);
  6. f: ARDS vs. normal oxygenation (P = 0.008);
  7. g: ARDS vs. normal oxygenation (P = 0.014), ARDS vs. simple hypoxemia (P = 0.004);
  8. h: ARDS vs. normal oxygenation (P < 0.001), ARDS vs. simple hypoxemia (P = 0.001);
  9. i: ARDS vs. normal oxygenation (P = 0.006), ARDS vs. simple hypoxemia (P = 0.006);
  10. j: ARDS vs. normal oxygenation (P = 0.001).