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Fig. 4 | Respiratory Research

Fig. 4

From: HMGB1-induced activation of ER stress contributes to pulmonary artery hypertension in vitro and in vivo

Fig. 4

TMP inhibits HMGB1-induced PASMC proliferation and migration via PERK/ATF4/SIAH2/HIPK2 axis. Cells were incubated with HMGB1 and TMP for 24 h. a PERK, ATF4, SIAH2 and HIPK2 expression were measured using western blotting. b Cell proliferation was determined by EdU incorporation assay. c Cell migration was detected using transwell assay. For original blot images, see Additional file 1. *P < 0.05

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Respiratory Research

ISSN: 1465-993X

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