Fig. 2
From: Collaborative cross strain CC011/UncJ as a novel mouse model of T2-high, severe asthma
CC011 mice have greater total lung resistance under both HDM and PBS conditions compared to BALB/cJ. Total lung resistance to increasing doses of methacholine. n = 3–6 HDM exposed and n = 3–4 PBS-exposed mice per strain. Within strain treatment contrasts from Welch’s one-sided t-test denoted by * for P < 0.05 and # for P < 0.1. Additional statistically significant (P < 0.05) differences between PBS exposed CC011 mice and both BALB/cJ treatment groups at 25 mg/ml methacholine are shown on the right