Table 1 Lung inflammation scoring of asthma and control mice after influenza infection
From: Chronic allergic asthma induces T-cell exhaustion and impairs virus clearance in mice
Score | Bronchiolar Infiltrate | Alveolar Involvement | |
|---|---|---|---|
Intraluminal Infiltrate | Peribronchial Infiltrate | ||
0 | None | None | None |
1 | ≦ 25% of visualized lumens; predominate mononuclear | Infiltrate ≦ 4 cells thick | Increased cellularity; no evidence of septal thickening |
2 | 25–50% of visualized lumens; mixed mono- and polymorphonuclear | Infiltrate 5–10 cells thick | Increased cellularity; no evidence of septal thickening |
3 | 50–75% of visualized lumens; predominately polymorphonuclear | 25–50% of visualized lumens | Significant celluarity, thickening; edema or blood, obliteration of < 25% of visualized alveolar space |
4 | Diffuse; predominately polymorphonuclear | Diffuse | Obliteration of > 25% of the alveolar space |