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Table 2 Polysomnographic characteristics of participants by intervention groups

From: Treatment of obstructive sleep apnea in high risk pregnancy: a multicenter randomized controlled trial

Polysomnographic parameter

CPAP group

N = 153

Usual-care group

N = 157

p value

Total sleep time (hour), mean (SD)

6.0 ± 1.0

6.2 ± 0.8

0.044

Sleep efficiency (%), mean (SD)

84.7 ± 11.6

85.9 ± 8.8

0.329

Sleep latency (minute), median (IQR)

14.4 (7.8, 25.7)

13.6 (7.5, 27.8)

0.730

Stage N1 and N2 (%), mean (SD)

62.6 ± 8.3

63.4 ± 8.3

0.371

Stage N3 (%), mean (SD)

20.6 ± 7.7

19.2 ± 7.3

0.085

Stage REM (%), mean (SD)

16.8 ± 5.0

17.4 ± 5.2

0.276

Sleep time during supine position (%), mean (SD)

69.1 ± 24.8

65.6 ± 24.2

0.080

Respiratory disturbance index (RDI)a (events/hour), mean (SD)

14.1 ± 6.6

14.9 ± 6.6

0.948

Apnea–hypopnea index (AHI)b (events/hour), median (IQR)b

7.0 (4.4, 12.5)

7.2 (4.4, 13.5)

0.813

Apnea index (events/hour), median (IQR)

0.2 (0.0, 1.2)

0.3 (0.0, 0.9)

0.262

Hypopnea index (events/hour), median (IQR)

6.4 (4.2, 10.1)

6.9 (4.0, 11.8)

0.453

Apnea–hypopnea index in REM sleep (events/hour), median (IQR)

16.1 (7.6, 31.3)

14.1 (7.6, 24.0)

0.249

Apnea–hypopnea index in NREM sleep (events/hour), median (IQR)

5.1 (2.6, 11.4)

6.8 (2.8, 11.8)

0.041

Apnea–hypopnea index during supine position (events/hour), median (IQR)

13.9 (9.5, 20.9)

15.6 (8.7, 21.2)

0.176

Apnea–hypopnea index during non-supine position (events/hour), median (IQR)

5.1 (2.6, 8.5)

5.1 (2.0, 10.2)

1.000

Oxygen desaturation indexc (events/hour), median (IQR)

1.9 (0.6, 4.3)

2.6 (0.9, 5.2)

0.372

Average oxygen saturation (%), mean (SD)

96.7 ± 1.1

96.6 ± 1.0

0.455

Minimum oxygen saturation (%), mean (SD)

89.4 ± 4.2

89.2 ± 3.9

0.686

Time oxygen saturation under 90% (minutes), median (IQR)

0 (0, 0.06)

0 (0, 0.07)

0.359

Obstructive sleep apnea characteristics

   

 Severityd, no. (%)

   

  Mild

71(46.4)

73(46.5)

0.987

  Moderate

82(53.6)

84(53.5)

 

In-laboratory polysomnography, no. (%)

152 (99.4)

156 (99.4)

1.0

Agreement between scorers (%), mean (SD)

89.0 ± 10.2

90.0 ± 11.8

0.433

  1. CPAP continuous positive airway pressure; IQR interquartile range; SD standard deviation
  2. aThe respiratory disturbance index (RDI) is the number of apnea, hypopnea and respiratory-event related arousal events per hour of sleep
  3. bThe apnea–hypopnea index is the number of apnea, and hypopnea events per hour of sleep
  4. cThe oxygen desaturation index is the number of times per hour of sleep during the oximeter recording that the oxygen saturation drops by at least 3 percentage points from baseline
  5. dSeverity of obstructive sleep apnea is classified as mild (respiratory disturbance index, RDI ≥ 5 and < 15 events/hour) and moderate (RDI ≥ 15 and < 30 events/hour)
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Respiratory Research

ISSN: 1465-993X

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