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Fig. 4 | Respiratory Research

Fig. 4

From: An ICD-Associated DAMP Gene signature predicts survival and immunotherapy response of patients with lung adenocarcinoma

Fig. 4

Comparison of the somatic mutation and immune landscape between DAMP-related subtypes. (A) Distinct somatic mutation profiles among the two subgroups. ns, not significant. (B) Estimation of immune scores, stromal scores, and tumor purity between two subgroups using the ESTIMATE algorithm. (C) Evaluation of immune cell proportions in two subgroups using the ssGSEA algorithm. (D) A Boxplot demonstrating gene distinct expression profiles of immune checkpoint genes in two subgroups. (E) Comparison of the TIDE score in two subgroups. P values were calculated using Wilcoxon rank sum test (*P < 0.05; **P < 0.01; ***P < 0.001, ****P < 0.0001)

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